Morgellons Researchers

The Origin of Morgellons

 

Nanomaterials and Cloning

 

Baculovirus expressions are designed to clone themselves by definition.  Just doing a search on ‘baculovirus and cloning’ on http://www.freepatentsonline.com we come up with 43,391 hits: http://tinyurl.com/y89kdjq

I have seen repeatedly in human and other samples where Morgellons starts with what is known as ’empty carbon cells’ in conjunction with an unidentified white, fuzzy  fungal growth similar to Pythium with white, red and blue hyphae, this a cultured human sample below:

This photo below is from fungus gnats eggs   that were harvested from an adult in my house:

These ’empty carbon cells’ aka as fullerenes then progress into the creation of the sphere capsids as seen below in this ‘thread’ that landed in someone’s yard in CT as part of a seeding program or are now found in nature. 

Back to a human sample below which shows this conversion from empty to capsid formation happening easier:

 

From articles and abstracts found in regard to fullerenes and human immunological involvement:

”Fullerene Nanomaterials Inhibit the Allergic Response

Fullerenes are a class of novel carbon allotropes that may have practical applications in biotechnology and medicine. Human mast cells (MC) and peripheral blood basophils are critical cells involved in the initiation and propagation of several inflammatory conditions, mainly type I hypersensitivity. We report an unanticipated role of fullerenes as a negative regulator of allergic mediator release that suppresses Ag-driven type I hypersensitivity. Human MC and peripheral blood basophils exhibited a significant inhibition of IgE dependent mediator release when preincubated with C60 fullerenes. Protein microarray demonstrated that inhibition of mediator release involves profound reductions in the activation of signaling molecules involved in mediator release and oxidative stress. Follow-up studies demonstrated that the tyrosine phosphorylation of Syk was dramatically inhibited in Ag-challenged cells first incubated with fullerenes. In addition, fullerene preincubation significantly inhibited IgE-induced elevation in cytoplasmic reactive oxygen species levels. Furthermore, fullerenes prevented the in vivo release of histamine and drop in core body temperature in vivo using a MC-dependent model of anaphylaxis. These findings identify a new biological function for fullerenes and may represent a novel way to control MC-dependent diseases including asthma, inflammatory arthritis, heart disease, and multiple sclerosis [1].”

What else can the immune system recognize?

One of the earliest challenges to our understanding of the molecular basis of the immune system was the system’s apparent unlimited capacity to bind essentially any chemical species, natural or synthetic, that it encounters.  Ideas of an “instructional” mechanism of attaining this broad spectrum of binding specificity have later on been excluded and replaced by an evolutionary selection process. More than 50 years ago, Karl Landsteiner, the pioneer of immunochemistry, already had recognized this feature. This observation later led to the conclusion that the immune system evolved the capacity to generate an adoptive repertoire of binding sites from which exposure to a given antigen will select the specific ones. Recent years of progress in chemistry now have presented the recognition spectrum of the immune system with both novel and more esoteric chemical entities. Scientists have raised antibodies that bind elementary carbon in fullerenes.

Fullerenes are highly ordered and symmetric molecules, with a structure known at the atomic resolution. It therefore is worthwhile to compare the capacity of vertebrate immune system to respond to other water-insoluble, ordered antigens. Water-insoluble crystals were found to be treated as antigens and when introduced into experimental animals are inducing specific antibodies. This property of the immune system has been recently illustrated by studies of Kessler et al., who raised and selected mAbs specific for crystals with well-defined structures at the molecular level of 1,4-dinitrobenzene. Significantly, none of these antibodies bound to the 1,4-dinitrophenyl hapten when it was conjugated to a protein carrier. An antibody interacting with a crystal may recognize a particular set of molecular components exposed on a specific crystal surface [6].”

Antibodies specific for fullerenes and their characteristics

The recent interest in using Buckminsterfullerene (fullerene) derivatives in biological systems raises the possibility of their assay by immunological procedures. This, in turn, leads to the question of the ability of these unprecedented polygonal structures, made up solely of carbon atoms, to induce the production of specific antibodies.

Until 1985 there were only two known allotropic forms of carbon: graphite and diamond. In 1985, a novel allotrope was reported in which 60 carbon atoms were arranged as a truncated icosahedron, with 60 vertices and 32 faces, 12 of which were pentagonal and 20 hexagonal.

It was dubbed Buckminsterfullerene (usually shortened to fullerene) because of its geodesic character, a name that has held through the present day.

[Considerable activity followed this discovery particularly after procedures were developed to prepare fullerenes in workable quantities. Various fullerene-based compounds have been prepared, and diverse uses were sought for them. Some were incorporated into photovoltaic cells  and nanotubes. Others were tested for biological activity, including antiviral, antioxidant and chemotactic activities, and as neuroprotective agents in a mouse model of amyotrophic lateral sclerosis.

Practical application of fullerenes as biological or pharmacological agents requires that dosage and serum levels be capable of measurement, preferably by sensitive, simple immunological procedures. This, in turn, requires that specific antibodies to fullerenes be produced.

The clonal selection theory tells us that antigens elicit the production of antibodies by selecting for specific antibody-producing cells already present in the repertoire of immunized animals. Although there is debate about the size of the “available” repertoire, immunologists usually work on the assumption that the repertoire is diverse enough to be counted on to produce antibodies to “any” molecule a researcher may choose. This is, of course, an unreliable assumption, as experimental failures rarely find their way into the literature. The question that arises, therefore, is whether the immune repertoire is “complete” enough  to recognize and respond to the unprecedented geodesic structure of the fullerenes or sufficient aspects of it—more particularly, whether the immune system can process a fullerene-protein conjugate and display the processed peptides for recognition by T cells to yield IgG antibodies. We report here that it does [3].”

Fullerene-like organization of HIV gag-protein shell in virus-like particles produced by recombinant baculovirus.

Virus-like particles produced by a recombinant baculovirus containing the HIV gag gene were examined by negative staining after delipidization.

This morphology and these dimensions indicate that the virus-like particles contain the gag precursor in the form of a near-spherical "fullerene-like" icosahedral shell. [2]”

A Fullerene-based Anticoagulant

This technology relates to the use of substituted or modified C60 fullerenes, which are carbon-based molecular cages that resemble soccer balls, for the prevention or treatment of thrombosis, peripheral arterial occlusion, and catheter obstruction [4] .”

Toxic Potential of Materials at the Nanolevel

Nanomaterials are engineered structures with at least one dimension of 100 nanometers or less. These materials are increasingly being used for commercial purposes such as fillers, opacifiers, catalysts, semiconductors, cosmetics, microelectronics, and drug carriers. Materials in this size range may approach the length scale at which some specific physical or chemical interactions with their environment can occur. As a result, their properties differ substantially from those bulk materials of the same composition, allowing them to perform exceptional feats of conductivity, reactivity, and optical sensitivity. Possible undesirable results of these capabilities are harmful interactions with biological systems and the environment, with the potential to generate toxicity. The establishment of principles and test procedures to ensure safe manufacture and use of nanomaterials in the marketplace is urgently required and achievable [5].”

I am stating that I believe the earlier photos that I have shown of baculovirus capsids are the same as what are known as fullerenes or Buckyballs.

References:

[1] The Journal of Immunology, 2007, 179, 665 –672 http://www.jimmunol.org/cgi/content/abstract/179/1/665

[2]  PubMed article 8259664 , Nermut MV, Hockley DJ, Jowett JB, Jones IM, Garreau M, Thomas D.

[3] B.-X. Chen*, S. R. Wilson, M. Das, D. J. Coughlin, and B. F. Erlanger*,

http://www.pnas.org/content/95/18/10809.full#xref-ref-5-1

[4] Pharmalicensing – Open Innovation for the life sciences

[5] Andre Nel,1,2* Tian Xia,1 Lutz Mädler,3 Ning Li1 http://www.sciencemag.org/cgi/content/abstract/311/5761/622

[6] David Izhaky* and Israel Pecht,

http://www.pnas.org/content/95/20/11509.full

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September 28, 2009 - Posted by | Uncategorized

8 Comments »

  1. I think this article made some interesting points, I read a textbook directly related to this topic, its called Chemistry: A Molecular Approach by , I found my used copy for less than the bookstores at http://www.belabooks.com/books/9780131000650.htm

    Comment by Amanda | September 30, 2009 | Reply

  2. Kammy,

    So you’re cultivating with Agar in petri? Are you using everything, or just the specks? White nits, flaky scales, threads (black, white, blue or red), reddish plastic gel blood substitute? How much material do you think would be needed to perform the southern or western blots? This current drift in research focus is inline with the initial reports that Dr. Hildy published as well, the baculovirus has definately been studied as an envelope for nanotech.

    Wyrmspear

    Comment by WyrmSpear | September 30, 2009 | Reply

  3. I don’t know If I said it already but …This blog rocks! I gotta say, that I read a lot of blogs on a daily basis and for the most part, people lack substance but, I just wanted to make a quick comment to say I’m glad I found your blog. Thanks, 🙂

    A definite great read..Jim Bean

    Comment by JimmyBean | October 1, 2009 | Reply

  4. Hi Wyrm,

    I’m not using fiber debris initially, but they appear later from the speck sources, fibers appear to be an end product.

    I’m not sure how much debris material would be needed for a Western Blot test, but I know I could easily produce enough.

    Comment by Kammy | October 1, 2009 | Reply

  5. Good to know, since this syndrome produces so much stuff… Still find it difficult to imagine someone telling folks it’s in their heads with the sheer amount of stuff this thing produces.
    I had another question, in regard to lesions or areas that produce stuff.. do you find that older scars and or areas where fibroblasts may have been active tend to produce more stuff than other areas? I.e. your head, is it in an area you may have had other wounds before, ie acne, sunburn or possibly precancerous tissue? It seems in my client that certain areas of prior injury seem to be areas where the fibers first make themselves known.

    Wyrmspear

    Comment by WyrmSpear | October 2, 2009 | Reply

  6. Hi Wyrm,

    I always look forward to your questions and comments, so nice. Of course, we all have opinions on how this ‘thing’ is operating inside our bodies from what we’ve experienced or experiencing and some of our opinions might differ? I know that there are some variations.

    Now that I believe I have found out what the actual ‘black speck’ part of our disease is, and there is something written about it that I just read, I should definitely make a blog article about it. Of course, the black specks tie into the biofilm and fibers, which I have shown.

    A lot of our fear comes from the fact that we don’t know what is or has happened to us. Most of us have spent our lifetimes building and looking out for our good health to now find that something very mysterious has robbed us. Naturally, we want to know what has caused our illness so that we can stop doing whatever it is, in hopes of getting better? It seems natural to think that because of the large volumes of debris that some of us can emit that the Morgellons pathogen is something that we are ingesting or coming into contact with on an ongoing basis and that if we keep re-introducing whatever it is… we will never get well? This not knowing is very concerning to the Morgellons sufferer and adds to our angst. I believe I can shed some light on what is happening though, from my recent experiences and observations and I will write about it shortly.

    I have believed from my experiences of how my Morgellons initially manifested itself in my body, coming out of my scalp, that it was something that I had ingested, I had a period of not feeling quite ‘right’ in my intestines before I had my initial outbreak. It seems to move from the intestines to the other organs and systems out through the skin and the pores of the scalp are the largest on the human body and that is why we hear so many that have it show initially this way. Of course, it is possible to contract Morgellons from someone who has bad lesions and if you contract it this way, yours might not show initially from the scalp? I also have changed how I view that Morgellons is contracted, I do not think that it has to be necessarily ingested.

    The lesions that are what I call the ‘producers’ have a core, or cone, that is either hard, rubbery, elastic, funnel-like and are very difficult to remove. I believe though that once this ‘cone’ is removed, the lesion no longer produces from this area? So, I cannot say that I agree with you on your statement above where you say, ‘do you find that older scars and or areas where fibroblasts may have been active tend to produce more stuff than other areas?’ I also just read something on how this ‘cone’ is known to operate within the furrelene which I will find and publish.

    I wonder about the ‘unusual’ that seems to manifest itself on the skin of the few people with Morgellons (from the scalp) that I have observed, such as the tiny raised red blood-filled bumps, and the very dark, black freckles, the white pox marks? I do believe that Morgellons is contagious in some cases and that how we initially contract it dictates our skin symptoms and that’s why we might see differences from person to person? Of course this is conjecture, until we can get more definitive answers.

    I’m wondering if the white pox marks on the arms are not a good indicator that one has the Morgellons pathogens in our systems? See what you notice there, Wyrm?

    Comment by Kammy | October 2, 2009 | Reply

  7. Kammy,

    I read an article from the m2.wordpress that mentioned the white pox. The white pigmentation changes that I’ve noticed seem more obvious in the abdominal area, where as area’s such as the arms and palms may have some pigmentation differences but not so readily apparent.
    Have you pre-bathed/showered with any of the probiotic or applecider vinegar treatments? This seems to bring forth alot of small boogerish white exudate that appears in nature as small sluggish nits, that slough off with the 75-100% vinegar. My thoughts were that this treatment would interrupt the life cycle. My previous opinion about the pigmentation changes were that they were visible signs of whatever this particular portion of the M lifecycle might be.
    The microangioma’s that I’ve observed occurred more in individuals that had not manifested the fibers but have some of the accompaning symptoms that have been noted. I was thinking that the pox might also be impacted lymphnodes, as many of the lesions seem to work their way to the surface in these areas, as well as various acupuncture tsubos along the meridians, perhaps guided by bioelectric impulse. The lesions often seem to manifest like infected hairs or whiteheads, and once they’ve made surface contain that tricky cone which appears as if it’s just the center of a zit but clings continually to one side and “bleeds” profusely if removed but not certain if what I’ve seen is actually blood as the dried components appear to spread out a little with the addition of small blistery new centers not far from the original. They also have the appearance of the dark freckle pigmentation that you speak of. This reminded me of the stealth virus theory I read about in march.
    Continual moisturization and use of additional essential oils tends to greatly assist with the itching sensations, associated skin damage as well as draw out the irritants to the epidermal layer. It certainly seems in many ways like someones science experiment made it out into the world, I do hope this hasn’t been intentional.

    Thanks for your energies and musings… I checked out the MRG site and I was quite put off by the bickering, so I might chime in if I notice a discussion that calls to me. I found the environment to be a bit childish considering the unknown nature of what we’re dealing with. I guess I’m just an optimist, expecting folks to work together.

    Later,
    WyrmSpear

    Comment by WyrmSpear | October 6, 2009 | Reply

  8. ”Have you pre-bathed/showered with any of the probiotic or applecider vinegar treatments? This seems to bring forth alot of small boogerish white exudate that appears in nature as small sluggish nits, that slough off with the 75-100% vinegar. My thoughts were that this treatment would interrupt the life cycle.

    Continual moisturization and use of additional essential oils tends to greatly assist with the itching sensations, associated skin damage as well as draw out the irritants to the epidermal layer.”

    Thanks for the tips, Wyrm… we never know when something we might recommend will bring much needed relief to someone suffering and at their wits end? I think this is a good recommendation, I got a lot of relief taking vinegar internally.

    ”Thanks for your energies and musings… I checked out the MRG site and I was quite put off by the bickering, so I might chime in if I notice a discussion that calls to me. I found the environment to be a bit childish considering the unknown nature of what we’re dealing with. I guess I’m just an optimist, expecting folks to work together.”

    Yes, isn’t it interesting how a few can be the promoters of so much disinfranchisement of so many? Such a sad state of affairs, to add more injury to the already so injured.

    Comment by Kammy | October 9, 2009 | Reply


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