Morgellons Researchers

Help With Morgellons Skin Lesions – Part 1

 

”Fullerene-based amino acid nanoparticle interactions with human
epidermal keratinocytes

Exposure to nanomaterials could occur through oral, dermal, inhalation, and injection routes, all of which could potentially initiate an adverse biological response.   Although little is known about the biological effects induced by exposure to nanoparticles, past research provides useful information for evaluating the potential hazards
associated with nanoparticle exposure.   Research involving fullerenes suggests that the underivatized C60 is cytotoxic to human liver carcinoma cells and fibroblasts (Sayes et al., 2004) and can induce oxidative stress in juvenile largemouth bass (Oberdorster, 2004).

The poor water solubility of fullerenes has limited research evaluating their biological interactions, since the water insolubility restricts pristine C60 from naturally interacting with biological substances.   However, the functionalization of C60 (i.e., the addition of amino acids, hydroxyl groups, carboxyl groups, etc.) can
increase the nanoparticles’ ability to interact with the biological environment ” 
[1].

Buckyballs made safer for humans

”The soccer-ball-shaped carbon nanoparticles were shown to cause brain damage in fish and kill water fleas in a study in March 2004. But now a team at Rice University in Houston, Texas, US, has come close to understanding how buckyballs – more formally known as fullerenes – kill cells and how their toxicity can be lowered in human cells.

Although the toxic nature of the carbon-60 nanoparticles may be useful in medicine, for example in fighting cancer, there are concerns that their potentially widespread use in fuel cells, drug delivery and cosmetics could mean they find their way into the environment, and so into animals and humans.

"There are a couple of different manufacturers that will, and are, mass producing fullerenes," says Christie Sayes, one of the team. "They could make it into consumer based products: fuel cells and batteries or make-up,"  she says.

Ruptured cells

The team, led by Vicki Colvin, looked at the effects of buckyballs on human cells. They found that even at quite low concentrations in water the buckyballs killed human skin cells. However, when they attached chemical groups such as hydroxyl groups to the buckyballs, their toxicity was greatly reduced.

The higher the number of groups that were attached, the less toxic the fullerenes became, so that a buckyball with 24 hydroxyl groups attached showed a toxicity seven orders of magnitude lower than the original buckyball.

The researchers believe the buckyball is toxic because in water it leads to the formation of an oxygen free radical which reacts with lipid molecules forming the cell membrane surrounding a cell. This causes the lipid molecules in turn to become free radicals – and when these try to interact with the water outside the cell, the membrane ruptures leading to cell death”  [2].

By looking at what I presented in the  blog article  ”The Origin of Morgellons”, where it is evident that we see Morgellons forming in 3 different  sources  with fullerene technology, knowing that another name for fullerenes is ‘buckyballs’ and from the above referenced article:

”when they attached chemical groups such as hydroxyl groups to the buckyballs, their toxicity was greatly reduced.”

Theoretically, the hydroxyl  group should help with our lesions.

References:

[1]. ScienceDirect, Toxicology in Vitro 20 (2006) 1313–1320, Jillian G. Rouse a,b, Jianzhong Yang c, Andrew R. Barron c, Nancy A. Monteiro-Riviere.

[2].  NewScientist Magazine article dn6458.

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October 2, 2009 - Posted by | Uncategorized

1 Comment »

  1. Very fine post……..
    This is a very good blog of uses of fullerenes and it’s uses on various ways as well as features. Issues discussed here like “Buckyballs made safer for humans” and “Ruptured cells” are really a very healthy knowledge to all…!!!

    Comment by Fullerene | November 13, 2009 | Reply


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